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Indigenous AmericanAndeanQuechua

Maca

Maca Root; Lepidium meyenii; Maca-maca; Ayak Chichira (Quechua). Often marketed as 'Peruvian Ginseng,' but that's just a marketing name; maca is a cabbage-family crop, not a ginseng.

A root vegetable in the cabbage family, native to the high Andes of central Peru and grown above 4,000 meters, where it's been a staple food and a stamina and fertility tonic for over a millennium.

FamilyBrassicaceae (cruciferous)
Part usedRoot (the swollen storage organ, eaten as a root vegetable).
OnsetFrom trials: sexual desire and function over 8 to 12 weeks; menopausal-life-stage well-being over 6 to 12 weeks. Onset varies by person, extract, and type.
Best timeMorning or early afternoon, to avoid disrupting sleep.

⚕ Educational content · traditional and historical use · not medical advice

Reproductive SupportMood SupportWomen's WellbeingEnergy
Glucosinolates (glucotropaeolin / benzyl glucosinolate, about 80 to 90 percent of total glucosinolates)macamides (N-benzyl fatty-acid amides, putative bioactives, formed during drying)macaenes (polyunsaturated fatty acids)imidazole alkaloids (lepidilines A and B)macahydantoins (thiohydantoin derivatives)macaridine. Notably NO phytoestrogens - consistent with the non-hormonal mechanism finding

A cruciferous (Brassicaceae) storage hypocotyl whose characteristic constituents include benzyl glucosinolates (glucotropaeolin), macamides (N-benzyl fatty-acid amides), macaenes, imidazole alkaloids (lepidilines A and B), and thiohydantoins (macahydantoins). Maca contains no known phytoestrogens (no isoflavones, lignans, or coumestans). Human studies (Gonzales 2002; Brooks 2008; Stojanovska 2015) consistently show no change in serum LH, FSH, prolactin, testosterone, or estradiol - i.e., the reported effects do NOT involve direct hormonal mechanisms or hormone replacement. This non-hormonal profile is a genuine, well-supported point of distinction.

Maca is endemic to the Meseta de Bombon / Junin-Pasco plateau of central Peru, between roughly 3,950 and 4,450 m - one of the highest-altitude cultivated food crops in the world. It is FIRST a food, second a medicine. The Spanish chronicler Cieza de Leon (1553) described root use "for maintenance"; Father Bernabe Cobo (1653) first recorded the name "maca" and its use for fertility; the 18th-century botanist Ruiz noted fertility and stimulant properties. The fertility tradition genuinely extended to LIVESTOCK - colonial pastoral records document maca being fed to introduced European animals that struggled to reproduce at altitude, so the human-and-animal fertility tonic use is a real documented Andean tradition, not a modern invention. Traditional preparation is always cooked: hypocotyls are boiled in water (the most frequent form), or made into mazamorra (porridge), chicha de maca (fermented drink), or roasted in huatia earth ovens. Raw maca powder is a modern (post-1990s) supplement form. Traditional intake in maca-growing communities exceeds 20 g/day of cooked product, versus about 1.5 to 3.5 g/day of powder in supplement trials - a gap that matters, because maca's strong safety record derives largely from food-level consumption of cooked product. The post-1990s commercialisation triggered biopiracy disputes: Pure World Botanicals obtained US patents (6,267,995; 6,428,824; 6,552,206) on maca extracts for sexual dysfunction; Peru's INDECOPI National Anti-Biopiracy Commission formally challenged them at the WTO (2006), and the case is widely cited as a motivating example for the Nagoya Protocol.

PowderCapsuleTabletLiquid Extract

Traditionally always cooked: boiled (most common), roasted in earth ovens, or made into porridge or a fermented drink. Modern forms include gelatinized (pre-cooked) powder, extract, and capsules. Raw maca powder is a modern form that can upset the stomach, so cooked or gelatinized forms are preferred.

With food for easier digestion. Gelatinized or cooked forms reduce the compounds that can upset the stomach.

Maca is a high-Andes food crop first and a fertility-and-stamina tonic second. Two honest points: the evidence is real but low-quality, with sexual desire (including antidepressant-related sexual problems) the best-supported use; and a genuine strength is that maca works without hormones (no phytoestrogens, and it doesn't change testosterone or estrogen levels). The California Prop 65 and goitrogen (thyroid) cautions are real; an earlier warfarin and bleeding warning was removed as unsupported. Not related to Asian ginseng.

⚠ Cautions & Contraindications

Cautions: Heavy-metal caution: maca grown in certain Peruvian soils can carry cadmium and lead above international limits, which is the real basis for California's Proposition 65 labeling, so choose tested products. Avoid during pregnancy and breastfeeding, since supplement-dose safety isn't established. Maca is in the cabbage family and contains goitrogens, but cooking (it's traditionally boiled) cuts these substantially, and there's no human thyroid trial. May cause headache or mood changes in some people. There's no documented blood-thinner interaction.

Contraindications: Use caution with hormone-sensitive cancers (a precaution per MSK, even though maca isn't estrogenic). Not enough safety data for supplement doses in pregnancy or breastfeeding (though it has a traditional food history). Avoid if you're allergic to maca or other cabbage-family plants.

  • Memorial Sloan Kettering About Herbs (Maca, last updated June 2023)
  • Kew Plants of the World Online (Lepidium meyenii Walp.)
  • World Flora Online
  • California OEHHA Proposition 65 (Cadmium, Lead)
  • PubMed: 38440178 (Ulloa Del Carpio 2024 review); 20691074 (Shin 2010 sexual-function systematic review); 21840656 (Lee 2011 menopause systematic review); 28811221 (Beharry & Heinrich 2018 critical review); 18801111 (Dording 2008 AISD men); 25954318 (Dording 2015 AISD women); 12472620 (Gonzales 2002 libido, no hormonal change); 11753476 (Gonzales 2001 sperm parameters); 18784609 (Brooks 2008 non-estrogenic postmenopausal); 24931003 (Stojanovska 2015 no hormonal action); 27548190 (Gonzales-Arimborgo 2016 mood / energy, COI disclosed); 21977053 (Gonzales 2012 ethnobiology review); 16174556 (Gonzales 2006 ecotypes, rodent); 15661081 (Gonzales 2005 prostate, rodent); 11754952 (Muhammad 2002 macamides); 12932133 (Cui 2003 lepidilines); 34401355 (Orellana-Mendoza 2021 Cd/Pb in Junin maca); 24915330 (cooking reduces glucosinolates); 24790635 (Ge 2014 - documents the ABSENCE of a maca-warfarin interaction)
  • PubMed Central: PMC10910417
  • PMC2928177
  • PMC4411442
  • PMC6494062
  • PMC3184420
  • PMC5039502

For informational purposes only. This entry does not constitute medical advice. Consult a qualified healthcare provider before starting any supplement, especially if you have existing health conditions, are pregnant or breastfeeding, or take prescription medications.

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Mended Remedies provides educational and informational content only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any remedy, supplement, or dietary change.